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Journal: Neuron

Article Title: Task-dependent changes in the large-scale dynamics and necessity of cortical regions

doi: 10.1016/j.neuron.2019.08.025

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Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Experimental Models: Organisms/Strains Mouse: C57BL6/J The Jackson Laboratory JAX: 000664 Mouse: B6.Cg-Tg(Slc32a1-COP4*H134R/EYFP)8Gfng/J The Jackson Laboratory JAX: 014548 Mouse: IgS6 tm93.1(tetO-GCaMP6f)Hze Tg(Camk2a-tTA)1Mmay/J The Jackson Laboratory JAX: 024108 Mouse: B6.129S2-Emx1 tm1(cre)Krj /J The Jackson Laboratory JAX: 005628 Mouse: B6.Cg-Tg(Thy1-YFP)HJrs/J The Jackson Laboratory JAX: 003782 Software and Algorithms Matlab 2015b, 2016b, 2017b Mathworks http://www.mathworks.com/products/matlab.html ViRMEn Aronov and Tank, 2014 https://pni.princeton.edu/pnisoftware-tools/virmen NI DAQmx 9.5.1 National Instruments https://www.ni.com/enus/support/downloads/drivers/download.ni-daqmx.html HCImage Hamamatsu https://hcimage.com Klusta Rossant et al., 2016 https://github.com/kwikteam/klusta Scanning laser control software This paper https://github.com/BrainCOGS/laserGalvoControl.git Other Virtual reality setup tools Pinto et al., 2018 https://github.com/sakoay/AccumTowersTools Open in a separate window KEY RESOURCES TABLE Mice navigated in virtual reality while performing one of three related tasks All dorsal cortex contributed to memory-dependent but not visually-guided navigation Higher task demands induced decorrelation of whole-cortical Ca 2+ activity patterns A modular RNN model suggested that differences in computations can explain results

Techniques: Software, Control